National Institute of Science Communication and Information Resources (NISCAIR , a constituent establishment of Council of Scientific & Industrial Research, is a premier Institute in Science Communication promoting science to diverse constituents at all levels using the most appropriate technologies. It provides formal linkages of communication among the scientific community in the form of research journals in differentareas of S&T, information on plant, animal and mineral wealth of the country; disseminate S&T information to general public including school students; harness IT applications in information management with particular reference to science communication and modernizing libraries; Act as facilitator in furthering economic, social, industrial, scientific and commercial development by providing timely access to relevant and accurate information; Develop HR in science communication, library, documentation and information science, and S&T information management systems and services, IPR, herbarium techniques, etc. The Institute also offers wide range of information products and services ranging from production of S&T publications, translation & interpretation of Scientific Documents from foreign languages to English. NISCAIR also undertakes projects in its area of activities
Applications are invited from the eligible citizens of India for filling up the following positions at
CSIR
-NISCAIR, New
Delhi
. Applicants are requested to carefully go through the full text of the advertisement regarding qualifications, subjects, fields of specializations and job requirements, etc. prescribed for each position and then fill up the online application form carefully. In case online submission is not possible, hardcopy will also be considered.
Post : Scientist / Senior Scientist
Post Code : 01
Stream :
Botany
/
Life Sciences
Essential Qualification : Ph.D. (Submitted in
Botany
/
Plant Sciences
Desirable : 1 Working knowledge in (i Indexing/classification/ abstracting; (ii S & T databases; (iii Computer Applications; (2 Proficiency in English
Post Code : 02
Stream :
Botany
/
Life Sciences
Essential Qualification : Ph.D. (Submitted in
Botany
/Life sciences/
Biochemistry
/
Plant Sciences
/ Biosciences
Desirable:
(1 Specialization in plant physiology/plant bio-chemistry /ethnopharmacology;
(2 Working knowledge in (i Scientific & Technical writing with published papers in peer reviewed journals; editing research papers, monographs & reviews; (ii Computer applications (2 Proficiency in English
Post Code : 03
Stream :
Botany
/
Life Sciences
Essential Qualification : Ph.D. (Submitted in
Botany
/ Agricultural Sciences / Life sciences/
Environmental Sciences OR ME/M. Tech in the relevant area
Desirable :
(1 Specialization in Ethnobotany/Anthropology; or Ethnobotany / Anthropology as one subject/course/paper in Post Graduation;
(2 Working knowledge in (i Scientific & Technical writing with published papers in peer reviewed journals; editing research papers, monographs & reviews; (ii Computer applications
(3 Proficiency in English
Post Code : 04
Stream :
Biotechnology
Essential Qualification : Ph.D. (Submitted in
Biotechnology
/Genetics/Life sciences/Biosciences /
Microbiology
/
Botany
/
Zoology
OR ME/M. Tech in the relevant area.
Desirable :
(1 Specialization in
Biotechnology
/Genetics or
Biotechnology
/Genetics as one subject/course/paper in Post Graduation;
(2 Working knowledge in (i Scientific & Technical writing with published papers in peer reviewed journals; editing research papers, monographs & reviews; (ii Computer applications
(3 Proficiency in English
How to Apply :
To apply, the applicants must fill in the online application form available at NISCAIR website
www.niscair.res.in Applications received electronically followed by hard copy attached with all relevant documents thereof, will be entertained. However, in case of nonavailability of online submission, application received in hardcopy only will also be accepted. Print out of duly filled online application form completed in all aspects and supported by attested copies of certificates in proof of educational qualifications, DOB, caste, experience, passport size photograph, etc. along with an application fee (Except SC, ST, PWD, female and regular employees of
CSIR
of Rs.100/- (Rupees One hundred only in the form of crossed Demand Draft/IPO valid for at least 6 months in favour of "The Director, NISCAIR, payable at New
Delhi
should be sent in sealed cover superscribed with “APPLICATION FOR THE POST OF SCIENTIST (Post code and category ” to The Controller of Administration, National Institute of Science Communication and Information Resources (NISCAIR , Pusa Campus, Dr. K.S. Krishnan Marg, New
Delhi
-110012, so as to reach on or before : 10.04.2012.
Deadline : 10.04.12
1Turning Point Alcohol and Drug Centre, Eastern Health and Monash University, Victoria, Australia
2Ambulance Victoria, Victoria, Australia
- Belinda Lloyd, Turning Point Alcohol and Drug Centre, 54?62 Gertrude Street, Fitzroy, VIC 3065, Australia. Email:
belindal@turningpoint.org.au
To the Editor
In the December 2010 issue,
Hollingworth
et al
. (2010 detailed increased prescribing of atypical antipsychotic medications in Australia between 2002 and 2007. While olanzapine and risperidone remain the most commonly prescribed atypical antipsychotics, quetiapine prescribing is increasing, with PBS prescriptions rising by 27% between 2008/09 (431,096 and 2009/10 (545,410 (
Department of Health and Ageing, 2010 . Reasons for the growing use (including off-label prescribing relate to its sedative properties and favourable extrapyramidal and metabolic profile, as well as emerging evidence of positive outcomes at low doses for a range of mental disorders (
Hollingworth et al., 2010 .
While the toxicity profile of atypical antipsychotics is considered preferable to typical agents, particularly regarding overdose risk, recent literature has called the relative safety of quetiapine into question. In one study, quetiapine-related overdoses were more likely to result in hypotension, respiratory depression, coma, or death than all the other antipsychotics combined (
Ngo et al., 2008 . This is particularly concerning given the growing number of case reports citing quetiapine as a potential substance of misuse, a phenomenon unseen with other atypical antipsychotic preparations (
Sansone and Sansone, 2010 .
A recent study (
Lloyd and McElwee, 2011 identified a non-significant increase in antipsychotic-related ambulance attendances over 2000?2009 in metropolitan Melbourne. While demographic characteristics remained relatively consistent over the period, there was a significant increase in antipsychotic-related attendances where other drugs (both licit and illicit were also implicated in presentations. However, differential harms across different antipsychotic preparations have not been adequately explored at a community level.
To further our understanding of this emerging issue, we analysed ambulance attendance data from metropolitan Melbourne across different antipsychotic preparations to provide a preliminary quantification of quetiapine-related harms. Data were derived from the Ambo Project database (
Lloyd and McElwee, 2011 , utilizing data from patient care records completed by paramedics, with additional coding undertaken to identify involvement of alcohol or other drugs in ambulance presentations. While there was a small increase in antipsychotic-related ambulance attendances between 2000/01 and 2009/10 (from 783 to 1074 attendances , quetiapine-related attendances increased substantially over the same period (from 32 in 2000/01 to 598 in 2009/10 . Similar increases were not found for other antipsychotic preparations.
Anecdotal reports from Victorian alcohol and drug agencies participating in the Earlier Identification of Drug Harms Project (unpublished data indicate that quetiapine demand, use, diversion, misuse, and harms are ongoing issues, particularly for clients with a history of illicit drug use. Over the course of this project involving bi-monthly data collection, quetiapine was the only antipsychotic consistently reported as being used in a problematic manner, regardless of source of supply.
Such an increase in acute quetiapine-related harm represents a growing public health issue. Further exploration is required to identify the nature and magnitude of quetiapine-related harms, population groups at increased risk of harm, prescribing trends, and strategies to ensure benefits of quetiapine are balanced against potential risks to patients, and costs to the community. In the meantime, it is important that clinicians are aware of growing misuse and diversion of quetiapine, and adopt prescribing practices that minimize the risk of harms.
Funding
This project is a collaborative project between Turning Point Alcohol and Drug Centre and Ambulance Victoria, and is funded by the Victorian Department of Health.
Acknowledgments
The authors would like to acknowledge and kindly thank Ambulance Victoria and its paramedics for their entry of data used in this study and Annie Haines for coding cases.
- © The Royal Australian and New Zealand College of Psychiatrists 2012
- ACS Applied Materials & Interfaces
- Bioanalytical Reviews
- Bioinspiration & Biomimetics
- Biomicrofluidics
- Bioprocessing
- Biotechnology and Bioprocess Engineering
- Current Trends in Biotechnology and Pharmacy
- Food Science and Biotechnology
- IEEE Transactions on Nanobioscience
- International IEEE/EMBS Conference on Neural Engineering
- Instrumentation Science & Technology
- Journal of Biomimetics, Biomaterials, and Tissue Engineering
- Journal of Biomolecular Techniques
- Journal of Nanoparticle Research
- Journal of Tissue Engineering and Regenerative Medicine
- Lasers in Medical Science
- Materials Science and Engineering: C, Materials for Biological Applications
- Minerva Biotecnologica
- Molecular Biotechnology
- Nano Letters
- NanoBioTechnology
- Romanian Biotechnological Letters
- Sensors
- Stem Cells and Cloning: Advances and Applications
- Tissue Engineering Part A
- Tissue Engineering Part B: Reviews
- Tissue Engineering Part C: Methods
- Wiley Interdiscipli
RESEARCH ADMISSION 2012 NOTIFICATION
INDIAN INSTITUTE OF TECHNOLOGY, MADRAS
The Indian Institute of Technology Madras (IITM is established as an autonomous institute of national importance in 1959 by the Government of India with an initial technical and financial support from Germany. IIT Madras with a number of well equipped laboratories, advanced research facilities, sophisticated services and computing and networking capabilities, is recognized to have done exceedingly well in the fields of higher technical education, research and industrial consultancy.
IIT Madras conducts academic programmes of
B.Tech
., Dual Degree (
B.Tech
. and
M.Tech
. , Integrated M.A,
M.Tech
., M.B.A,
M.Sc
., M.S. and Ph.D. in various disciplines. Located in about 225 hectares of natural flora and fauna, with 17 student's hostels and about 1000 faculty/staff quarters, IIT Madras is one of the greenest residential campuses in the country. Faculties of international repute, a brilliant student community, excellent technical and supporting staff and an effective administration have all contributed to the pre-eminent status of IITM.
Categories of admission in Ph.D programme :
a Regular full-time scholars with or without Institute fellowship or with project support.
b Research scholars sponsored under the Quality Improvement Programme (QIP .
c Research scholars who are staff members of the Institute
d Research scholars under the external registration programme sponsored by and employed in industry/orgainsation having R & D facilities and recognised by DST or IIT Madras, national laboratories, reputed universities/colleges or employed in research/analysis jobs in public sector/private sector/government in the case of management area. (A research scholar under the external registration programme will normally carry out part or all of his / her research work in the industry/organization/national laboratories/universities employing the scholar under the supervision of a co-guide also employed in the same organization and a guide at IIT Madras. The candidate must have at least two years experience in the case of registration in Engineering/Sciences/Social Sciences/ Management.
e Research scholars working on a part-time basis from a reputed University/Institution/ Organisation. They should have two years experience for registration in Engineering, Sciences and Humanities & Social Sciences Depts./Department. (A research scholar working on a part time basis shall normally carry out the research work at IIT Madras under the supervision of a guide at IIT Madras. The feasibility of doing this with sufficient intensity will be an important consideration in admitting the scholar in this category .
f Candidates applying for admission in the External/Part-time categories:
i Should submit a relief certificate at the time of admission
ii Should submit one page write-up about the research topic.
iii Must belong to any one of the following category:
a Industry/organization having R& D facilities and recognized by DST, GoI or IIT Madras
b National Laboratories
c Reputed Universities / Colleges
d Public sector / Private sector / Government Departments engaged in research/analysis jobs of their executives in the case of management area.
g The minimum residential requirement for the Ph.D scholar under external registration and Ph.D. research scholars working on part-time basis not employed in the Institute is one semester.
Eligibility :
Biotechnology
: Masters Degree in Engineering / Pharmacy / Science
Important Dates :
- Registration of Application forms will be open on : 26.02.2012
- Last date for Registration of application through on-line : 26.03.2012
- Interview and or Test [on or before]* : 21.05.2012 to 25.05.2012
- Selected Candidates to join on : 16.07.2012
* Intimation on interview and/or test indicating the date of interview will be given by the respective Departments.
Deadline : 26.03.12
Telegraph. The supervisors of one trial noted, “It was rather common for patients to claim significant insights into their problems, to feel that they had been given a new lease on life, and to make a strong resolution to discontinue their drinking.” In the 70s, governments began crackdowns on any aspect of LSD being clinically studied and research was left incomplete and shelved. None of the experiments that were begun featured enough patients to draw any firm conclusions, however a reanalysis of all the data taken together suggests the compound could have potential after all. A study, presented in the Journal of Psychopharmacology, looked at data from six trials with 536 patients and it said there was a “significant beneficial effect” on alcohol abuse, which lasted several months after as little as one dose was taken. LSD is one of the most powerful hallucinogens ever identified. It appears to work by blocking serotonin in the brain, which controls functions including perception, behavior, hunger and mood, reports
BBC News. For the group of patients taking LSD, 59 percent showed reduced levels of alcohol misuse compared with 38 percent in the other group. This effect was maintained for up to six months after taking the hallucinogen, but it disappeared after a year. The report’s authors, Teri Krebs and Pal-Orjan Johansen, told BBC News: “A single dose of LSD has a significant beneficial effect on alcohol misuse,” and suggested that more regular doses might lead to a sustained benefit. Norwegian researcher and fellow of Harvard Medical School, who led the research, Pal-Orjan Johansen said in a recent press statement: “Given the evidence for a beneficial effect of LSD on alcoholism, it is puzzling why this treatment approach has been largely overlooked.” Dr. David Nutt, former advisor on drugs to the government, told The Telegraph: “I think this study is very interesting and it is a shame the last of these studies were done in the 1960s.” “I think these drugs might help people switch out of a mindset which is locked into addiction or depression and be a way of helping the brain switch back to where it should be, in a similar way that Alcoholics Anonymous programs do.” For the moment, studying human behavioral responses rather than brain chemistry may be more helpful in understanding how the drugs work, writes Arran Frood for
Nature. Robin Carhart-Harris, a psychopharmacologist at Imperial College London who has researched how psilocybin could treat depression, told Frood that psychedelics must work at both biological and psychological levels. “Psychedelics probably work in addiction by making the brain function more chaotically for a period — a bit like shaking up a snow globe — weakening reinforced brain connections and dynamics,” he said. --- On the Net:
For instance, some investigators, such as Ronald Duman of Yale University, are focusing on finding compounds that will kick in more quickly in our bodies.
Duman and his colleagues are trying to learn lessons from ketamine, an anesthetic and painkiller that is also sold illicitly under the name "Special K." The group has shown in rats that ketamine rapidly causes neurons to make new contacts with one another and, apparently by so doing, produces antidepressant effects. Based on an understanding of the molecular basis of those changes, the researchers are now looking for safer agents that operate in a similar way.
NPR. "We're not talking about abandoning standards for safety and efficacy, we're talking about leveraging opportunities in science so we can do a more effective job as regulators and also improve the drug development process." The agency said eliminating or reducing the number of routine visits to the doctor could free up prescribers "to spend time with more seriously ill patients, reduce the burdens on the already over burned health care system and reduce health care costs." Drugmakers would have to request a switch for each drug individually, and the FDA would judge the safety of each proposal on a case-by-case basis. "We're not talking about very specific drugs right now, we're talking about the concept," Dr. Janet Woodcock, director of FDA's drug center, told NPR. --- On the Net:
No comments:
Post a Comment